Margaret Brown Kilik was raised by a single mother, and they moved frequently throughout the country during her childhood. Kilik graduated from the University of Toledo with a degree in English and subsequently lived in San Antonio, where she renewed a relationship with Eugene Kilik, whom she married. They spent the majority of their lives in New York City, where Kilik established and ran the Key Gallery in Soho. She was a collage artist and writer, and her only novel, The Duchess of Angus, written in the early 1950s, was discovered after her death. She died in New York in 2001.